Im currently taking it but ny insurance doesn't cover qysemia so i take phentermine 37.5 mg in the a.m & topiramate 50 mg before bed the only side effects with I experience with phentermine is increased heart rate, sweating, and dry mouth which is good because im drinking at least a gallon of what a day. The first week I experienced headaches but I found out that was an indication to drink water or eat something. I barely had an appetite and had to remind myself at times to eat. The topiramate make my mouth extremely dry and drowsy that why I take it before bed, fogged memory was also a side effect the first week but eventually went away. I started the 1st 2 months on the low dose taking only half 37.5 mg & 25 mg weighing 297 im currently 288 this is the 1st week of month 3 on full dose